- Secrets of Magonia – v1.03
- Seed of Life
- Seed of the Dead: Sweet Home – v1.03 R/v1.03 + Uncensoring/Adult Patch
- Sekiro: Shadows Die Twice – Game of the Year Edition – v1.06 + Bonus Content
- Selene’s Unbearable Night – v1.0 (Release)
- Self-Isolation
- Selfloss
- Sengoku Dynasty – v1.0.0.3 + Bonus Content
- SENRAN KAGURA Bon Appetit! – Full Course – v1.01.05
- SENRAN KAGURA Burst Re:Newal – Tailor-Made Limited Edition
- Senran Kagura Estival Versus + 13 DLCs
- SENRAN KAGURA Peach Ball + 4 DLCs
- SENRAN KAGURA Peach Beach Splash – v1.01 + 28 DLCs
- SENRAN KAGURA Reflexions + 20 DLCs
- Senran Kagura Shinovi Versus
- Sentinel
- Senua’s Saga: Hellblade II – v1.0.0.0.158523
- September 7th
- Serial Cleaners
- Serin Fate – v1.0.0.0
- Serious Sam 2 – v2.90 (Mar 23, 2021)
- Serious Sam 3: BFE v233089 + Jewel of the Nile DLC
- Serious Sam 4: Digital Deluxe Edition – v1.08 / Build 591667 + DLC + Bonus
- Serious Sam HD: The Second Encounter – Build 263699 + All DLCs
- Serious Sam: Siberian Mayhem – v610302 + LAN Multiplayer
- Serious Sam: Tormental – v1.0.217
- Session: Skate Sim – v1.0.0.32 Release + 2 DLCs
- Seven: Enhanced Collector’s Edition – v1.3.2 + Bonus Content
- Severed Steel
- Sex Chess – Build 9917588
- Sexy Beach Premium Resort v1.11 + 14 DLC
- SGS NATO’s Nightmare
- Shadow Complex Remastered
- Shadow Corridor 2 – v1.04 + Windows 7 Fix
- Shadow Gambit: The Cursed Crew – Supporter Edition – v.1.0.52.r37952.f + Bonus Content
- Shadow Gambit: The Cursed Crew – Supporter Edition – v.1.0.52.r37952.f + Bonus Content
- Shadow Man: Remastered – v1.0.2261
- Shadow of Ether
- Shadow of the Tomb Raider: Definitive Edition – v1.0.449.0_64 + All DLCs + Bonus Content
- Shadow Tactics: Aiko’s Choice – v3.2.25.F.r4769
- Shadow Tactics: Blades of the Shogun – v1.1.2.f
- Shadow Warrior 2: Deluxe Edition, v1.1.14.0 + 9 DLCs + Bonus Content
- Shadow Warrior 3: Digital Deluxe Edition + DLC + Bonus Content
- Shadow Warrior: Special Edition v1.5.0
- Shadow Watcher
- Shadowed Descent
- Shadowrun: Hong Kong
- Shadows of Doubt – v39.07
- Shadows of the Damned: Hella Remastered
- Shadows: Awakening – v1.1